""My, it's unusual to see a boy your age here. Are you a customer?""

- Amane

Amane is Yukiyo's mother and Mei and Misaki's maternal grandmother. She is the receptionist of the doll shop owned by her daughter, Yukiyo, named Misaki M. Studio.

Amane has gray shoulder-length hair and gray eyes. She also wears glasses with round lenses and dark purple clothes. In the manga, she has white, shoulder-length hair and black clothes. Also, her spectacles are black with square lenses. Amane looks older in the manga than in the anime.

Amane appears to suffer from some form of dementia. She never seems to move from her seat at the front of the store and doesn't remember Kōichi, even though he constantly visits her shop, as she repeats the same questions every time he enters.

Amane made her debut in "Blueprint" when she welcomes Kōichi Sakakibara after he tried to follow Mei and discovered the doll shop. Every time she sees him, Amane repeats the same phrases. She is always shown sitting at the reception desk of the doll shop when Kōichi visits Mei. Later, Kōichi finds out that Amane is Mei's grandmother.