Mieko Sakuragi (桜木 美恵子, Sakuragi Mieko) is the deceased mother of Yukari Sakuragi.

In the manga, Mieko has black shoulder-length hair that is similar to Sanae Mizuno's hairstyle, and her eyes aren't shown. Her appearance in the anime is unknown, as she doesn't physically appear.

Mieko was in a car, along with Yukari's aunt and possibly her sister, when it had an accident. Mieko died, becoming the first known "death of May." When one of her male relatives (possibly her father) arrived to tell Yukari and take her to the hospital, a distraught Yukari panicked and fled, encountering Kōichi and Mei at a stairwell. Running away, she fell down the stairs and impaled herself on her umbrella, dying mere hours apart from her mother.

Meiko never appears but is mentioned in the anime.

In the manga, the cause of her death is never revealed, although oddly, this is the only place she appears, as a picture can be seen of her alongside her daughter at the memorial.